Why lower body tempeture during....?

Q1: Why does lowering a patients body temperature during convinced types of surgical procedures actually increase the possibility of the surgery being successful?

Q2 : Why are prolonged elevated fevers existence threatening?


Answers:    I think that the types of procedure you're referring to are probably ones where on earth part of the body is temporarily deprived of bloodflow and consequently oxygen. The cold slows down cellular metabolism and prevents the defacement that would otherwise occur.

This impair is caused by diverse factors. One is the switch to anaerobic (air-free) metabolism which produces lactic bitter. (this is why your muscles burn after an aerobic exercise where you body have trouble supplying enough oxygen). Another is that stressed cell self-destruct through a process called apoptosis. Related to this - apoptotic cell trigger your immune system (which normally cleans up unmoving cells) to release free radicals an enzymes which can despoil surrounding cells. Lastly, fast reintroduction of oxygen to cells which own been deprived can incentive a "respiratory burst" which releases damaging free radical. These can in turn trigger apoptosis.

As next to most of biology, all these phenomenae are adjectives connected, and affect each other. What the cold does, is essentially put everything within "slow motion" so that the surgeons have time to do what they stipulation to do before too much defacement is done.

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